Poten-Cee + ZN Advance

Ascorbic acid (as Sodium ascorbate) + Zinc + Cholecalciferol (Vitamin D₃) (POTEN-CEE + ZN ADVANCE) Capsule is an off-white to yellowish white crystalline powder encapsulated in a slightly soft and slightly brittle empty gelatin capsule size #00 with scarlet opaque cap and body.
Each capsule contains 562.43 mg of Sodium ascorbate (equivalent to 500 mg of Ascorbic acid), 70 mg of Zinc gluconate (equivalent to 10 mg Zinc) and 1,000 IU of Vitamin D₃.

Vitamins/Mineral.
Poten-Cee + ZN Advance (Vitamin C + Zinc + Vitamin D₃), combines active ingredients that play critical roles in immune function, inflammatory response, and collagen synthesis.
Vitamin C, Vitamin D, and Zinc play synergistic roles in supporting components of both innate and adaptive immunity, making them an ideal combination of immunity-boosters. Deficiency of these have been associated with higher susceptibility to infectious diseases caused by bacterial, fungal, and viral pathogens such as colds and flu. Together, they have been shown in a meta-analysis to shorten the duration of acute respiratory tract infection by 6% to 59%, helping fast recovery. Vitamin C, including its non-acidic format Sodium ascorbate, is well known for its immune-boosting properties for colds and flu. Vitamin D₃ (cholecalciferol) supplementation is protective against acute respiratory tract infections in deficient populations. Zinc is essential for the Zinc-dependent metallopeptidase STEP protein, which can inhibit viral cell entry and restrict a wide range of viruses, hence acting as a wide-spectrum anti-viral protein.
Vitamin C, Vitamin D, and Zinc together help the body's natural defense against damaging free radicals (antioxidant effect). Free radicals are associated with aging and various chronic diseases. They are highly reactive and unstable chemicals generated during normal body activities that require oxygen (e.g., respiration, digestion, blood circulation, immune system response, increased physical activity, etc.) and after exposure to UV light, cigarette smoke and various pollutants. Vitamin C is a potent anti-oxidant in humans. Zinc supplementation has been shown to decrease oxidative stress and inflammatory cytokines in the elderly. Vitamin D₃ helps to protect the skin against hazardous effects of skin aging-triggering agents, including UV radiation, pollution, and microbial infections.
Vitamin C and Zinc also function as cofactors of enzymes involved in collagen formation and synthesis. Collagen is an important protein that can be used by the body for growth and repair of tissues and necessary for healthy skin, hair, bones, and joints. It provides strength and elasticity to the skin and promotes faster wound healing. Vitamin D₃ plays an important role in calcium homeostasis and bone metabolism and its deficiency can lead to bone growth abnormalities such as osteomalacia and rickets.

Ascorbic acid (as Sodium ascorbate) + Zinc + Cholecalciferol (Vitamin D₃) (POTEN-CEE+ ZN ADVANCE) Capsule is used for the prevention and treatment of Vitamin C, Zinc and Vitamin D₃ deficiencies as well as the maintenance and support of immune system function.

Take 1 capsule daily or as prescribed by a physician.
What Should the Patient Do if They Miss a Dose: If the patient misses a dose, they may take it as soon as they remember. However, if the patient remembers it at a time that is already close to the next dose, just skip the missed dose and take the next dose as scheduled. Do not take two doses of the medicine at the same time.

Signs and Symptoms of Overdose: Vitamin C: If the patient takes too much Ascorbic acid, they may experience signs and symptoms of toxicity like nausea, vomiting, indigestion, diarrhea, flushing of the face, headache, fatigue and disturbed sleep.
Zinc: Rare occurrences of acute zinc poisoning have been reported. The toxicity signs observed after ingestion of high zinc dose (4-8 g) include nausea, vomiting, diarrhea, fever, metallic taste and lethargy (sleepiness).
Vitamin D₃: Weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, metallic taste, nausea, vomiting and others.
What to Do if The Patient has Taken More Than the Recommended Dosage: If the patient has taken more than the recommended dose of this medicine and they are experiencing adverse symptoms, seek medical attention immediately.

Do not take this medicine if the patient is hypersensitive to Ascorbic acid, Zinc, Vitamin D or any component of the product.

Consult the doctor before taking this medicine if the patient has hyperoxaluria (an excessive excretion of oxalate in the urine) or a condition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Inform the physician before use if the patient is on a sodium-restricted diet.
Do not take more than the recommended dose.
Consult the physician if any adverse effect occurs.
When Should the Patient Consult the Doctor: If the symptoms persist or worsen after a few days of taking this medicine, or if the patient believes they are experiencing an adverse reaction to this medicine, it would be best to consult the doctor as soon as possible.

Vitamin C: Vitamin C toxicity is very rare because the body cannot store the vitamin and immediately excretes it in urine. However, if the patient takes amounts greater than 2,000 mg/day, they may experience stomach upset and diarrhea. The daily use of high doses may lead to the formation of oxalate stones in the kidneys. The patient may also experience disturbed water and electrolyte balance in their body, increased hemolysis (breaking-up of red blood cells), increased calcium in the kidneys, and suppression of cobalamin (Vitamin B₁₂) activity. If the patient has a condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency, taking too much Vitamin C can cause hemolysis which may cause them to feel tired, or dizzy, or even cause them to be anemic. In some rare cases, the patient may experience painful urination or pink/bloody urine. If any of these effects persist, tell the doctor immediately. For women who take high doses of Vitamin C during pregnancy, the babies may develop 'rebound scurvy' after birth and require immediate Vitamin C supplementation.
Zinc: Gastrointestinal side effects such as nausea and vomiting are seen with doses of elemental zinc greater than 40 mg.
Vitamin D₃: Serious side effects of Vitamin D₃ include, but are not limited to: Allergic reactions like rash or itching; Swelling of the face, throat, and tongue; Severe dizziness; Trouble breathing; Changes in heart rhythm including irregular or racing heartbeat.
Rare side effects of Vitamin D₃ include: Dry mouth; Headache; Vomiting; Weakness and lack of energy; Fatigue.

Vitamin C: Concurrent intake of more than 200 mg of Ascorbic acid per 300 mg of elemental iron would increase absorption of iron from the intestines. Increased urinary excretion of Ascorbic acid and decreased excretion of aspirin occur when the patient takes these drugs together. Taking Ascorbic acid with paracetamol can prolong the presence of paracetamol in the blood. Ascorbic acid is not compatible in solution with drugs like aminophylline, bleomycin, erythromycin, lactobionate, nafcillin, sodium nitrofurantoin, conjugated estrogens, sodium bicarbonate, sulfafurazole, diethanolamine, chloramphenicol sodium succinate, chlorothiazide sodium and hydrocortisone sodium succinate. Ascorbic acid has also been reported to interfere with blood-thinning treatments. Consult the doctor for advice before taking Ascorbic acid if the patient is taking any of the previously-mentioned medications.
Zinc: Zinc is known to have medicinal interactions with certain classes of antimicrobials like cephalosporins, beta-lactam antibiotics, tetracyclines, antiretroviral drugs like atazanavir, ritonavir, antineoplastic agents like cisplatin, antidiabetic drugs like glimepiride, glyburide, pioglitazone, insulin and potassium-sparing diuretics like amiloride. The presence of other medical problems like copper deficiency may make the condition worse. Discuss with the physician the use of the medicine with food, alcohol, or tobacco.
Vitamin D₃: The patient should avoid taking Vitamin D₃ if they are taking the following drugs: Paricalcitol; Calcipotriene; Doxercalciferol; Mineral oil; Orlistat; Bile acid sequestrants like colesevelam, colestipol, cholestyramine.
Drugs like Orlistat, or bile acid sequestrants like those listed previously can decrease or prevent the body from absorbing Vitamin D₃ and other fat-dependent vitamins (A, E, and K).
Take Vitamin D₃ at least 2 hours apart from the previously-mentioned list of drugs or take the Vitamin D₃ at bedtime to allow enough time to avoid interactions.
Also, be careful with drugs like: Digoxin; Aluminum hydroxide; Water pills like chlorthalidone, hydrochlorothiazide and chlorothiazide; Magnesium hydroxide and Magnesium citrate; Fosphenytoin.

The patient should keep this medicine at temperatures not exceeding 30°C and protect it from heat and direct sunlight.

Vitamins &/or Minerals

A11JB - Vitamins with minerals ; Used as dietary supplements.

Non-Rx