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Recent MI or Stroke or Established Peripheral Arterial Disease: Recommended Dose: Orally, 75 mg once daily with or without food.
Prophylaxis of Thromboembolic Events: Usual Dose: Orally, 75 mg once daily.
Non-ST Segment Elevation Acute Coronary Syndrome (Unstable Angina/non-Q Wave MI): Initiate a single 300-mg loading dose and then continue at 75 mg once daily in combination with aspirin.
A higher bleeding risk associated with combined use of clopidogrel and aspirin. It is recommended that physicians monitor their patients through clinical and laboratory evaluation.
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