Platexan Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Clopidogrel bisulfate

Indications/Uses

Reduction of atherothrombotic events in patients w/ history of recent MI/stroke or established peripheral arterial disease; MI & stroke in patients w/ non-ST-segment elevation acute coronary syndrome [(ACS) unstable angina/non-ST-elevation MI (NSTEMI)] including patients who are to be managed & those who are to be managed w/ coronary revascularization.

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Dosage/Direction for Use

ACS Initially, single 300-mg oral loading dose & continue at 75 mg once daily. Recent MI/stroke, or established peripheral arterial disease 75 mg once daily orally w/o loading dose.

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Overdosage

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Active pathological bleeding eg, peptic ulcer or intracranial hemorrhage.

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Special Precautions

Hypersensitivity including rash, angioedema or hematologic reaction to other thienopyridines; diminished antiplatelet activity in patients w/ impaired CYP2C19 function; increase risk of bleeding; discontinue if there is an increased risk of CV events; TTP. Severe & moderate renal impairment. Hepatic impairment. Pregnancy category B. Lactation. Safety & efficacy have not been established in childn. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Chest pain, accidental/inflicted injury, flu-like symptoms, pain, fatigue. Edema, HTN.

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Drug Interactions

Avoid concomitant use w/ omeprazole or esomeprazole due to the reduction of antiplatelet activity. Increase risk of GI bleeding w/ NSAIDs; warfarin; SSRIs & SNRIs. Increase systemic exposure w/ repaglinide.

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Storage

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Description

View Platexan description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)

ATC Classification

B01AC04 - clopidogrel ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.

Regulatory Classification

Presentation/Packing

Form

Platexan tab 75 mg

Packing/Price

30's (P817.6/pack)

Platexan

clopidogrel

Manufacturer:

Samjin

Distributor:

Patriot