Pantor-20/Pantor-40/Pantor IV Dosage/Direction for Use

Pantor-20/Pantor-40: Pantoprazole (Pantor-20/Pantor-40) Enteric-Coated tablets should be swallowed whole, with or without food in the stomach. If patients are unable to swallow a 40 mg tablet, two 20 mg tablets may be taken. Concomitant administration of antacids does not affect the absorption of Pantoprazole sodium enteric-coated tablets.
Short-Term Treatment of Erosive Esophagitis Associated with Gastroesophageal Reflux Disease (GERD): Adults: 40 mg once daily up to 8 weeks*.
Children (5 years and older): >15 kg to <40 kg: 20 mg once daily for up to 8 weeks.
>40 kg: 40 mg.
* For adult patients who have not healed after 8 weeks of treatment, an additional 8-week course may be considered.
Maintenance of healing of erosive esophagitis and reduction in relapse rates of daytime and nighttime heartburn symptoms in adult patients with gastro-esophageal reflux disease (GERD): Adults: 40 mg once daily**.
**Controlled studies did not extend beyond 12 months.
Long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome: Adults: 40 mg twice daily***.
***Dosage regimens should be adjusted to individual patient needs and should continue for as long as clinically indicated. Doses up to 240 mg daily have been administered.
Prophylaxis for NSAID-associated ulceration: The recommended adult oral dose of pantoprazole is 20 mg once daily.
Eradication of Helicobacter pylori: Pantoprazole may be combined with two antibacterials in a 1-week triple therapy regimen.
Effective regimens include pantoprazole 40 mg twice daily combined with clarithromycin 500 mg twice daily and either amoxicillin 1 g twice daily or metronidazole 400 mg twice daily.
Peptic Ulcer Disease: 40 mg once daily. Treatment is usually given for 2 to 4 weeks for duodenal ulceration, or 4 to 8 weeks for benign gastric ulceration.
Administration in Hepatic Impairment: Dosage may need to be reduced in severe hepatic impairment, or doses given only on alternate days. A maximum dose of 20 mg daily, or 40 mg on alternate days.
Administration in Renal Impairment: Maximum dose of 40 mg should be observed.
Pantor IV: The recommended dosage is one vial per day administered over 2 to 15 minutes.
Pantoprazole should be reconstituted with 10 mL of physiological sodium chloride solution into the vial containing the dry substance. The solution may be administered directly.
DIRECTION FOR USE: Dissolve the contents of the vial with given sterile Sodium Chloride Injection USP and use immediately. Use the ampoule only once and discard the ampoule.