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Pantoprazole + Domperidone (PANTOKEM-D) shall be given with care to patients with renal dysfunction or hepatic dysfunction.
Pantoprazole: Not recommended in child <12 yrs. Long-term therapy may lead to bacterial overgrowth in the GIT.
Domperidone: Increases serum prolactin levels resulting to galactorrhoea in females and gynaecomastia in males. Hypertensive crisis in patients with pheochromocytoma.
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