Onabet Description

Each g of cream contains: Sertaconazole Nitrate BP 20 mg, Cream base q.s.
Sertaconazole nitrate (Onabet) cream, 2% is for topical application. It contains the azole antifungal, sertaconazole nitrate. Sertaconazole nitrate contains one asymmetric carbon atoms and exist as a racemic mixture of equal amounts of R and S enantiomers. Sertaconazole nitrate is designated chemically as (±)-1-[2,4-dichloro-β-[7-chlorobenzo[b]thien-3-yl)methoxy]phenethyl]imidazole nitrate.
It has a molecular weight of 500.8.
The molecular formula is C₂₀H₁₅Cl₃N₂OS·HNO₃.
Sertaconazole nitrate is a white or almost white powder. It is practically insoluble in water, soluble in methanol, sparingly soluble in alcohol and in methylene chloride.
Each gram of Sertaconazole nitrate cream, 2%, contains 17.5 mg of sertaconazole (as sertaconazole nitrate, 20 mg) in a white cream base.
Excipients/Inactive Ingredients: Preservative: Benzyl Alcohol BP 10 mg.
Cream base: Ethylene glycol, glyceryl isostearate, glycolized saturated glycerides, light mineral oil, methylparaben, polyethylene glycol palmitostearate, polyoxyethylened saturated glycerides, sorbic acid and purified water.