Norizec Adverse Reactions

Metabolic-Nutritional: Hypoglycemia, hyperglycemia, syndrome of inappropriate antidiuretic hormone (SIADH) secretion, aggravation of diabetes mellitus, hyponatremia, increased appetite, anorexia, weight gain.
Gastrointestinal (GI): Diarrhea, nausea, vomiting, heartburn, abdominal discomfort, abdominal distention, abdominal pain, gastrointestinal pain, dyspepsia, sensation of fullness, metallic taste.
Cardiovascular: Bradycardia, palpitations, vasodilation.
Hematologic: Anemia (aplastic and hemolytic), leukopenia, granulocytopenia, agranulocytosis, thrombocytopenia (including severe cases with platelet count less than 10,000 microL), thrombocytopenic purpura, erythrocytopenia, pancytopenia.
Immune System Disorders: Leukocytoclastic vasculitis, hypersensitivity reactions worsening (e.g., dyspnea, fall in blood pressure, and shock); cross-sensitivity reaction to other sulfonylureas may also occur.
CNS: Disulfiram-like reactions, headache, dizziness, insomnia, tremor, paresthesia, nervousness, dry mouth, hot flashes.
Hepatobiliary: Cholestasis, jaundice, abnormal liver function, hepatitis which may lead to liver failure or hepatic dysfunction, hepatic porphyria reactions, increased liver enzyme levels.
Skin and subcutaneous tissue disorders: Allergic or pseudo-allergic reactions (e.g., pruritus, rash, urticaria, erythema multiforme, erythema nodosum, urticaria, morbilliform, maculopapular skin eruptions), Stevens-Johnson Syndrome (SJS), exfoliative dermatitis, porphyria cutanea tarda, photosensitivity reactions.
Urogenital: Increased urinary frequency, nocturia.
Miscellaneous: Asthenia, pain in extremity, allergic vasculitis, sweating, visual disturbance/abnormal vision, flu syndrome, accidental injury, laboratory test abnormal, decrease in serum sodium concentration.