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One case of deliberate overdosage with Clopidogrel has been reported. A 34 year old woman took a single 1,050 mg dose of Clopidogrel (equivalent to 14 standard 75 mg tablets). There were no associated adverse events. No special therapy was instituted, and she recovered without sequelae.
However, based on biological plausibility, platelet transfusion may be appropriate to reverse the pharmacological effects of Clopidogrel if quick reversal is required.
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