The most frequent events are headache, dizziness, peripheral oedema, palpitations and flushing
Tabulated List of Adverse Reactions: Adverse reactions listed below have been observed during clinical studies and/or during marketed use and are based on clinical trial data and classified according to MedDRA System Organ Class. Frequency categories are defined according to the following convention: very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,00 to <1/100); rare (≥1/10,000 to < 1/1,000); very rare (< 1/10,000) and not known (cannot be estimated from the available data.) (See table.)

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