Combination with beta-blockers: Caution should be exercised when using nicardipine in combination with a beta blocker in patients with decreased cardiac function. In such case, the posology of the beta blocker should be individualized to the clinical situation.
Injection site reactions: Infusion site reactions can occur, particularly with prolonged duration of administration and in peripheral veins. It is advised to change the infusion site in case of any suspicion of infusion site irritation. The use of a central venous line or of a greater dilution of the solution could reduce the risk of occurrence of infusion site reaction.
Excipient warnings: This product contains sorbitol. Patients with rare hereditary problem of fructose intolerance should not take this medicine.
Use in Children: The safety and efficacy of nicardipine IV has not been tested in controlled clinical trials in infants or children, thus special care is required in this population.
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