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Neuromuscular blocking agents (e.g., Tubocurarine chloride, Metocurine iodide, Pancuronium bromide, and Vecuronium bromide) may be enhanced by high doses of Vitamin B1 (>500 mg daily), although the clinical significance of this is unknown.
Take this medicine (Neurogen-E) at least two hours before or after taking Phenobarbital or Phenytoin since high doses of Vitamin B6 may reduce the blood levels of these drugs.
Concomitant intake of anticoagulants (e.g., warfarin, aspirin, etc.) and Vitamin E may result in enhanced anticoagulant (blood thinning) response.
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