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Nifedipine should be used with caution in patients whose cardiac reserve is poor.
Nifedipine should be discontinued immediately if hypersensitivity reaction occurs.
In patients with impaired liver function, careful monitoring and, in severe cases, a dose reduction may be necessary.
Impairment of Fertility: In single cases of in vitro fertilization, calcium antagonists eg, nifedipine, have been associated with reversible biochemical changes in the spermatozoa's head section that may result in impaired sperm function.
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