Drug interaction studies have been performed in adults only.
Antitussive drugs and mucolytic agents like Acetylcysteine should not be concurrently administered because the reduction in cough reflex could lead to the accumulation of bronchial secretions.
Concurrent administration of Nitroglycerin and Acetylcysteine has been shown to cause significant hypotension and enhance temporal artery dilation. If concurrent nitroglycerin and acetylcysteine therapy is necessary, patients should not be monitored for hypotension, which can be severe and warned of the possibility headaches.
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