Mucoprotec Special Precautions

Use in pregnancy: Reproductive and developmental studies conducted in rats showed no toxic effects on reproductive outcome, and fetal development, however since the safety of Rebamipide in human pregnancy has not been established, it should not be used in pregnant women or among those who are suspected to be pregnant except in clinical circumstances where there is no appropriate alternative therapy.
Use in lactation: In animal studies, Rebamipide has been reported to be excreted in breast milk and should not be administered to nursing mothers until its safety among breastfeeding infants has been clarified.
Use in Children: The safety of Rebamipide in pediatric patients has also not been established and therefore should not be used in these patients.
Use in the Elderly: The adverse events and its frequency of occurrence among the elderly are no different from those that are observed in younger patients but because of the changes in physiologic functions observed in elderly patients, caution should still be taken when administering the drug in this population group with special attention given to the occurrence of gastrointestinal adverse events.