Sign Out
Acetylcysteine should be used with caution in asthmatic patients and those with a history of peptic ulcer disease, both because drug-induced nausea and vomiting may increase the risk of gastrointestinal haemorrhage in patients predisposed to the condition, and because a theoretical risk that mucolytics may disrupt the gastric mucosal barrier.
The total clearance of acetylcysteine in patients with cirrhosis was found to be markedly impaired, and the elimination half-life almost twice that of healthy controls, hence, an increased vigilance for untoward anaphylactoid reactions and other adverse effects for these patients.
Use in Pregnancy & Lactation: See USE IN PREGNANCY & LACTATION section for further information.
Continue with Google