Epilepsy or history of CNS disorders, impaired hepatic or renal function, G6PD deficiency or myasthenia gravis. Discontinue if patients experience tendon pain, inflammation or rupture. Risk of crystalluria; maintain adequate fluid intake & avoid excessive urine alkalinity. Avoid exposure to excessive sunlight or sunlamps. May impair ability to drive or operate machinery. Pregnancy & lactation. Childn & adolescents.