Montemax Mechanism of Action

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Full Prescribing Info

Action

Pharmacokinetics: Peak plasma concentrations of montelukast are achieved in 2-4 hrs after oral administration. The mean oral bioavailability is 64%, montelukast is >99% bound to plasma proteins. It is extensively metabolized by cytochrome P450 isoenzymes CYP3A4, CYP2A6 and CYP2C9 and is excreted principally in the feces via the bile. Metabolism was reduced and the elimination t_½ prolonged in patients with mild to moderate hepatic impairment.

montelukast

Manufacturer:

Natrapharm

Distributor:

Natrapharm