Methycobal Caution For Usage

Precautions concerning Use: Tablet: For drugs that are dispensed in a press-through package (PTP), patients should be instructed to remove the drugs from the package prior to use. Swallowing the PTP sheet by mistake may cause puncture in the esophageal mucosa due to sharp corners of the sheet, resulting in perforation and in serious complications such as mediastinitis.
Injection: Administration: Mecobalamin (METHYCOBAL) is susceptible to photolysis. It should be used promptly after the package is opened, and caution should be taken so as not to expose the ampoules to direct light.
Intramuscular administration: In intramuscular administration, caution should be exercised by following the instructions mentioned as follows to avoid adverse effects on tissues or nerves: Avoid repeated injection at the same site. Particular caution should be exercised when administering Mecobalamin (METHYCOBAL) to low-birth weight babies, neonates, nursing infants and children.
Do not inject in densely innervated site.
If insertion of the injection needle causes intense pain or if blood flows back into the syringe, withdraw the needle immediately and inject at a different site.
Opening the ampoule: Mecobalamin (METHYCOBAL) is supplied in one-point-cut ampoules. The cut point of the ampoules should be wiped with an alcohol swab before opening.
Precaution for Handling: Caution: Mecobalamin (METHYCOBAL) is packaged in the LPE (Light Protect Easy open pack) to ensure quality during storage. The LPE pack should be opened immediately before using.