Meromax 500/Meromax 1000 Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Meropenem

Indications/Uses

Intra-abdominal infections, gynaecological infections, meningitis, resp tract infections (including in cystic fibrosis patients), septicaemia, skin & structure infections, UTI & infections in immunocompromised patients.

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Dosage/Direction for Use

Adult Pneumonia, UTI, gynaecological infections, skin & skin structure infections 500 mg IV every 8 hr. Nosocomial pneumonia, peritonitis, presumed infections in febrile neutropenic patient, septicaemia 1 g every 8 hr. Meningitis 2 g every 8 hr. Childn >50 kg Adult dose, >3 mth up to 12 yr 10-20 mg/kg IV every 8 hr. Meningitis 40 mg/kg IV every 8 hr. Febrile episodes in neutropenic patient 20 mg/kg every 8 hr. Renal insufficiency CrCl 26-50 mL/min Recommended dose every 12 hr, 10-25 mL/min ½ recommended dose every 12 hr, <10 mL/min ½ recommended dose every 24 hr.

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Overdosage

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Contraindications

Hypersensitivity.

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Special Precautions

Critically ill patients w/ known or suspected Pseudomonas aeruginosa lower resp tract infection (as monotherapy). Previous hypersensitivity reaction to β-lactams. Discontinue use if an allergic reaction occurs. Overgrowth of nonsusceptible organisms w/ prolonged use. Pseudomembranous colitis. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Pains, inflammation, thrombophlebitis at the site of inj; urticaria, rash, pruritus, erythema multiforme, TEN & SJS; nausea, vomiting, abdominal pain, diarrhoea, pseudomembranous colitis; increased eosinophils, reversible thrombocythaemia, thrombocytopenia, leucopenia, neutropenia, agranulocytosis, +ve direct or indirect Coombs' test, shortened partial thromboplastin; increased transaminases, alkaline phosphatase, LDH & bilirubin; paraesthesia, headache, seizures; rarely, systemic allergic reaction (hypersensitivity), angioedema & anaphylaxis; oral & vag candidosis.

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Drug Interactions

Inhibited renal excretion resulting to increased plasma conc & prolonged elimination t_½ w/ probenecid. Reduced serum levels of valproic acid to subtherapeutic levels.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Meromax 500/Meromax 1000 detailed prescribing information

Storage

View Meromax 500/Meromax 1000 storage conditions for details to ensure optimal shelf-life.

Description

View Meromax 500/Meromax 1000 description for details of the chemical structure and excipients (inactive components).

Action

View Meromax 500/Meromax 1000 mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Meromax 1000 powd for IV inj 1 g

Packing/Price

1's

Form

Meromax 500 powd for IV inj 500 mg

Packing/Price

1's

Meromax 500/Meromax 1000

meropenem

Manufacturer:

Biolab

Distributor:

Cathay Drug