Mep-40 Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Omeprazole

Indications/Uses

Reflux oesophagitis; acid-PUD; Zollinger-Ellison syndrome; adjunctive in duodenal ulcers associated w/ H. pylori combined w/ appropriate antibiotics; prophylaxis of acid aspiration before surgery; prevention & treatment of NSAID-associated ulcers.

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Dosage/Direction for Use

Relief of acid-related dyspepsia 10 mg or 20 mg daily for 2-4 wk. Treatment of GERD 20 mg once daily for 4 wk. Refractory oesophagitis 40 mg daily. Maintenance therapy: 20 mg once daily. For acid reflux: 10 mg daily. PUD 20 mg once daily or 40 mg once daily for severe cases, continue treatment for 4 wk for duodenal ulcer & 8 wk for gastric ulcer. Maintenance dose: 10-20 mg once daily. Treatment of NSAID-associated ulceration 20 mg once daily. Prophylaxis Patient w/ previous history of gastroduodenal lesions who require continued NSAID treatment 20 mg daily. Zollinger-Ellison syndrome Initially 60 mg once daily, majority of patients are effectively controlled by doses between 20-120 mg daily. Prophylaxis of acid aspiration during general anesth 40 mg in the evening before surgery & a further 40 mg 2-6 hr before the procedure.

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Overdosage

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Administration

Should be taken on an empty stomach.

Contraindications

Hypersensitivity to omeprazole & substituted benzimidazoles.

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Special Precautions

Consider possibility of malignancy before giving to patients w/ gastric ulcers as these may mask symptoms & delay diagnosis. Caution in hepatic impairment.

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Use In Pregnancy & Lactation

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Adverse Reactions

Headache, diarrhea & skin rashes. Pruritus, dizziness, fatigue, constipation, nausea & vomiting, flatulence, abdominal pain, arthralgia & myalgia, urticaria & dry mouth.

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Drug Interactions

May prolong elimination of diazepam, phenytoin & warfarin. Can reduce absorption of ketoconazole & possibly itraconazole.

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Storage

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Description

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Action

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MIMS Class

Antacids, Antireflux Agents & Antiulcerants

ATC Classification

A02BC01 - omeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

Regulatory Classification

Presentation/Packing

Form

Mep-40 cap 40 mg

Packing/Price

30's

Mep-40

omeprazole

Manufacturer:

Hizon

Distributor:

Pharma Dynamic