Painful neurological manifestations such as neuritis, polyneuritis, neuralgia, lumbago, ischialgia, sciatica, cervical and shoulder arm syndrome.
Neuropathies associated with certain disease states such as diabetes mellitus and cardiac disorders; alcoholic neuropathy; iatrogenic complications arising from INH, reserpine, and phenothiazine therapy; other drug induced neuropathies, neuropathic changes during pregnancy, hyperemesis gravidarum.
Prophylaxis and treatment of nutritional megaloblastic anemia associated with folic acid deficiency, as in hemolytic anemia, pernicious anemia, alcoholism, and that following gastrectomy.
Prevention of neural tube defects.
As adjunct in the treatment of colorectal carcinoma, ulcerative colitis, sickle cell diseases, and homocysteinemia.
To correct decreased folate levels when taking the following: Methotrexate, trimethoprim, sulfamethoxazole, phenytoin, and oral contraceptive pills.
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