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Lipway: Inadvisable Combinations: Other fibrates, HMG CoA reductase inhibitors: risk of additive undesirable muscular effects.
Combination requiring precautions: Oral anticoagulants increased effect of oral anticoagulants and greater risk of haemorrhage (through displacement of their plasma protein binding).
The INR should be monitored more frequently and the dosage of oral anticoagulants adjusted during and for 8 days after withdrawal of the treatment of with fenofibrate. The same of supervision is indispensable when switching to another fibrate, as the degree of potentiation is variable from one product to another.
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