Liosal Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Baclofen

Indications/Uses

Symptoms of spasticity from multiple sclerosis, particularly for relief of spasm & concomitant pain clonus & muscular rigidity. Dystonia; spasticity associated w/ cerebral palsy; trigeminal neuralgia.

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Dosage/Direction for Use

Initially 5 mg tid for 3 days, increased to 10 mg tid for 3 days, then in similar increment & interval until 20 mg tid is reached or desired therapeutic effect is obtained. Childn Initially 2.5 mg given qid, increased about 3 days until desired therapeutic effect is obtained. Maintenance dose: 6-10 yr 30-60 mg daily, 2-6 yr 20-30 mg daily, 12 mth-2 yr 10-20 mg daily.

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Overdosage

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Administration

Should be taken with food.

Contraindications

Hypersensitivity. Epilepsy, rheumatic muscle spasm, preexisting bladder sphincter hypertonia.

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Special Precautions

Patients w/ history of peptic ulcer; severe psychiatric disorders or epilepsy or convulsive disorders; resp impairment; DM; cerebrovascular disease; who use their spasticity to maintain posture or increase function. Avoid use in patients w/ active PUD. Monitor liver function in patients w/ liver disease. May exacerbate urine retention in patients w/ hypertonic bladder sphincters. Avoid abrupt w/drawal; gradually reduce dose over at least 1-2 wk. May affect ability to drive or operate machine. Renal impairment. Pregnancy. Not recommended during lactation. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Drowsiness, nausea, dizziness, lassitude, lightheadedness, confusion, fatigue, muscular pain & weakness, & hypotension.

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Drug Interactions

CNS effects may be exacerbated w/ alcohol & other CNS depressants. Severe aggravation of hyperkinetic symptoms may occur w/ lithium. May increase weakness w/ TCA. May increase hypotensive effect of antihypertensives. Excretion may be reduced leading to toxicity w/ ibuprofen & other drugs producing renal insufficiency.

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Storage

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Description

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Action

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MIMS Class

Muscle Relaxants

ATC Classification

M03BX01 - baclofen ; Belongs to the class of other centrally-acting muscle relaxants.

Regulatory Classification

Presentation/Packing

Form

Liosal FC tab 10 mg

Packing/Price

20's

Liosal

baclofen

Manufacturer:

Delta Pharma

Distributor:

Biomed