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Clarithromycin is a macrolide derived from erythromycin with similar actions and uses. It is given in the treatment of infections such as:
a. Respiratory tract infections (e.g. pharyngitis/tonsillitis caused by Streptococcus pyogenes, acute maxillary sinusitis, chronic bronchitis, pneumonia) including otitis media.
b. Skin and soft tissue infection caused by Staphylococcus aureus, Streptococcus pyogenes.
c. For prophylaxis and treatment of opportunistic Mycobacterial infections commonly caused by Mycobacterium kansasii, Mycobacterium avium or Mycobacterium intracellulare and for the treatment of leprosy.
d. For the prevention of disseminated infection due to Mycobacterium avium (MAC) in patients with advanced HIV infection.
e. Protozoal infection, including toxoplasmosis.
f. Clarithromycin may be given to eradicate Helicobacter pylori in the treatment regimens for peptic ulcer disease.
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