Ketosolv Drug Interactions

The simultaneous administration of medicaments containing calcium (e.g., acetolyte) may lead to pathological increase of the serum calcium level or intensification. As the uraemic symptoms improve under Ketoanalogues + Essential amino acids, a possible administration of aluminum hydroxide should be reduced. Pay attention to a reduction of serum phosphate. In order not to interfere with absorption, do not take Ketoanalogues + Essential amino acids together with drugs that form sparingly soluble compounds with calcium [e.g., tetracyclines, quinolone (e.g., ciprofloxacin, norfloxacin), iron, fluoride, and estramustine-containing drugs]. Between the intake of Ketoanalogues + Essential amino acids and drugs from the mentioned categories, a period of at least 2 hours should pass. The susceptibility towards heart/cardiac-active glycosides and hence also the risk of arrhythmia increase with the rise of the blood calcium concentration.