Kenzamide Adverse Reactions

Tablet: The most common side-effect associated with Furosemide therapy is fluid and electrolyte imbalance including hyponatraemia, hypokalaemia and hypochloraemic alkalosis, particularly after large doses or prolonged administration. Because of their shorter duration of action, the risk of hypokalaemia may be less with loop diuretics such as Furosemide than with thiazide diuretics. Unlike the thiazide diuretics, Furosemide increases the urinary excretion of calcium. Nephrocalcinosis has been reported when Furosemide has been used to treat preterm infants.
Furosemide may provoke hyperglycaemia and glycosuria, but probably to a lesser extent than the thiazide diuretics. It may cause hyperuricaemia and precipitate attacks of gout in some patients. Signs of electrolyte imbalance include headaches, hypotension, muscle cramps, dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, oliguria, cardiac arrhythmias and gastrointestinal disturbances.
Other side-effects are relatively uncommon and include blurred vision, yellow vision, dizziness, headaches and orthostatic hypotension. Skin rashes and photosensitivity reactions, although rare, may be severe and hypersensitivity reactions including interstitials nephritis, vasculitis and fever occur rarely. Pancreatic is more common at high doses and cholestatic jaundice has been reported. Bone marrow depression may occur rarely: agranulocytosis, thrombocytopenia and leucopenia have been reported. Tinnitus and deafness may rarely occur in particular during rapid high-dose parenteral Furosemide therapy. Rarely, deafness may be permanent particularly if Furosemide has been given to patients taking other ototoxic.
Injection: Nausea, vomiting, diarrhea, indigestion, visual disturbance, tinnitus, transient hearing impairment, muscle spasm, paresthesia, orthostatic hypotension, pancreatitis, hepatic dysfunction, photosensitivity, dizziness, fatigue, muscular weakness, increased thirst and impulse to urinate, rarely skin rash, myelopathy (leukopenia, thrombocytopenia). Disturbance of electrolyte and fluid balance, particularly hypokalemia may occur.
Inform a doctor in case of any adverse reactions related to drug use.