Each film coated tablet contains: Cefuroxime (as Axetil) 500 mg.
Antibacterial.
Pharmacology: Pharmacokinetics: Cefuroxime Axetil is absorbed from the gastrointestinal tract and is rapidly hydrolysed in the intestinal mucosa and blood to cefuroxime; absorption is enhanced in the presence of food. Peak plasma concentrations are reported about 2 to 3 hours after an oral dose. It is widely distributed in the body including pleural fluid, sputum, bone, synovial fluid, and aqueous humour, but only achieves therapeutic concentrations in the CSF when the meninges are inflamed. It crosses the placenta and has been detected in breast milk. It is excreted unchanged, by glomerular filtration and renal tubular secretion, and high concentrations are achieved in the urine.
It is a second generation cephalosporin antibiotic used in the treatment of susceptible infections such as bone and joint infections, bronchitis (and other lower respiratory-tract infections), gonorrhea, meningitis, otitis media, peritonitis, pharyngitis, sinusitis, skin and soft tissue infections, urinary tract infections and for surgical infection prophylaxis.
Usual oral doses for adults are 125 mg twice daily for uncomplicated urinary tract infections and 250 to 500 mg twice daily for respiratory tract infections. Or as prescribed by the physician.
Should not be given to patients who are hypersensitive to it or to other cephalosporins. Care is also necessary in patients with a history of allergy.
Gastrointestinal disturbances, including diarrhea, nausea, and vomiting have occurred in some patients receiving cefuroxime axetil. There have been rare reports of erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis.
Probenecid reduces the renal clearance of cefuroxime.
Store at temperature not exceeding 30°C.
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Jyscef FC tab 500 mg
10's
Sign Out
Continue with Google
Sign up with email
Already a member?
Sign in
