Isoket IV Use In Pregnancy & Lactation

Fertility: There are no relevant data available.
Use in Pregnancy: Isosorbide Dinitrate (Isoket) should only be used in pregnancy if, in the opinion of the physician, the possible benefits of treatment outweigh the possible hazards.
No data have been reported which would indicate the possibility of adverse effects resulting from the use of Isosorbide Dinitrate (Isoket) in pregnancy. Safety in pregnancy, however, has not been established.
Use in Lactation: Isosorbide Dinitrate (Isoket) should only be used during lactation if, in the opinion of the physician, the possible benefits of treatment outweigh the possible hazards.
Available evidence is inconclusive or inadequate for determining infant risk when used during breastfeeding. There is data that nitrates are excreted in breast milk and may cause methaemoglobinemia in infants. The extent of excretion of isosorbide dinitrate and its metabolites in human breast milk has not been determined. Therefore, caution is appropriate when administering this agent to lactating women.