Use in pregnancy. Drugs that act directly on the renin-angiotensin system can cause fatal and neonatal morbidity and death when administered to pregnant women. When pregnancy is detected, irbesartan should be discounted as soon as possible.
Use in lactation:The excretion of irbesartan in breast milk has not yet been established. In a study done in animals, irbesartan was found to pass into the milk of lactating rats. Thus, caution should be taken when adminstering Irvex to lactating mothers.
                                
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