Inhibita Dosage/Direction for Use

Benign gastric and duodenal ulcers including NSAID induced gastric and duodenal ulcers or gastro duodenal erosions: 20 mg once daily for 4 weeks in duodenal ulceration or 8 weeks in gastric ulceration, in severe cases the dose may be increased to 40 mg daily.
Gastro esophageal reflux disease (GERD): 20 mg once daily for 4 weeks, followed by a further 4-8 weeks if not fully healed; 40 mg daily has to be given for 8 weeks in patients with reflux oesophagitis refractory to other therapy. Patients can be continued at a dosage of 20 mg once daily.
Acid related dyspepsia: the usual dose is 20 mg once for 2-4 weeks depending on the severity and persistence of symptoms. Patients who do not respond after 4 weeks or who relapse shortly afterwards, should be investigated. Zollinger-Ellison Syndrome: Initially 60 mg once daily; usual range 20-120 mg daily (above 80 mg in 2 divided doses). Larger doses of up to 180 mg daily in divided doses may be used.
Helicobacter pylori eradication regimens in peptic ulcer disease: recommended dose is 40 mg once daily in association with antimicrobial drugs as described as follows: *Triple therapy regimens: Omeprazole 20 mg twice daily with one of the following antimicrobial combinations- Amoxycillin 500 mg & Metronidazole 400 mg both 3 times a day for one week, or Clarithromycin 250 mg and Metronidazole 400 mg (or Tinidazole 500 mg) both twice a day for one week or Amoxycillin 1 g and Clarithromycin 500 mg both twice a day for one week.