Infen-25 Adverse Reactions

Following are the adverse reactions reported as at least possibly related with dexketoprofen trometamol.
Common: Nausea and/or vomiting, abdominal pain, diarrhoea, dyspepsia.
Uncommon: Sleep disorder, anxiety, headache, dizziness, vertigo, palpitations, flushing, gastritis, constipation, dry mouth, flatulence, rash, fatigue, pain, asthenia, malaise, rigors.
Rare: Paraesthesia, syncope, hypertension, bradypnoea, peptic ulcer, peptic ulcer haemorrhage or peptic ulcer perforation, urticaria, acne, increased sweating, back pain, polyuria, menstrual disorder, prostatic disorder, peripheral oedema, liver function test abnormality.
Very rare: Neutropenia, thrombocytopenia, anaphylactic reaction, including anaphylactic shock, blurred vision, tinnitus, tachycardia, hypotension, bronchospasm, dyspnoea, pancreatitis, hepatocellular damage, Stevens Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), angioneurotic oedema, facial oedema, photosensitivity reactions, pruritus, nephritis or nephrotic syndrome.
The following undesirable effects may appear because they have been observed with other non-steroidal anti-inflammatory drugs and may be associated with prostaglandin synthesis inhibitors: aseptic meningitis, which might predominantly occur in patients with systemic lupus erythematosus or mixed connective tissue disease; and haematological reactions (purpura, aplastic and haemolytic anaemia, and rarely agranulocytosis and medullar hypoplasia), bullous reactions in Stevens Johnson Syndrome and Toxic Epidermal Necrolysis (very rare). Clinical trial and epidemiological data suggest that use of some NSAIDs (particularly at high doses and in long term treatment) may be associated with a small increased risk of arterial thrombotic events (for example myocardial infarction or stroke).