Immunosin Mechanism of Action

Immunostimulant.
Pharmacology: Pharmacodynamics: Inosine dimepranol acedoben is used in the treatment of a variety of viral infections. It acts by modifying or stimulating cell-mediated immune processes rather than acting directly on the virus.
In vitro exposure of cells to inosine dimepranol acedoben induces T-lymphocyte differentiation and potentiation of induced lymphoproliferative responses. The drug modulates T-lymphocyte and natural killer cell cytotoxicity, suppressor and helper cell functions. It also increases the number of IgG and complement surface markers. Interleukin-1 and -2 production, and neutrophil, monocyte and macrophage chemotaxis and phagocytosis are also potentiated by Inosine dimepranol acedoben.
In vivo antiviral and possible antitumor activity of inosine dimepranol acedoben is believed to result from enhancement of host immune responses. The drug does not by itself stimulate resting lymphocytes but augments immunological processes by lymphocytes once they have been triggered by mitogens or viral agents.
Pharmacokinetics: Inosine dimepranol acedoben is rapidly and completely absorbed (≥90%) from the gastrointestinal tract with peak plasma concentrations occurring 1 hr after an oral dose. It is also rapidly metabolized with a plasma half-life (t_½) of 50 min. The Inosine dimepranol acedoben portion of the complex yields uric acid and the other components undergo oxidation and glucuronidation. The metabolites are excreted in the urine.