May exacerbate inflammatory conditions of the skin, including chronic graft versus host disease. Discontinue for severe vulvar swelling. Consider interruption of dosing if systemic reactions occur. Minimize or avoid natural or artificial sunlight exposure. Actinic keratosis; other types of basal cell carcinoma including nodular & morpheaform (fibrosing or sclerosing) types; superficial basal cell carcinoma lesions on the face, head & anogenital area. Pregnancy & lactation. Childn.