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Indications and Dosage
Mouth/Throat
Aphthous ulcer, Gingivitis, Mouth infections, Oral hygiene, Sore throat Adult: As 0.1% solution: Rinse or gargle with at least 15 mL of undiluted solution bid or tid. Do not swallow; spit out after use. Treatment recommendations may vary among countries or individual products (refer to local or specific product guidelines).
Child: As 0.1% solution: ≥12 years Same as adult dose. |
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What are the brands available for Hexetidine in Philippines?
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Other Known Brands
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Special Precautions
Not intended to be swallowed. Children. Pregnancy and lactation.
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Adverse Reactions
Gastrointestinal disorders: Nausea, vomiting, dry mouth, ageusia, dysphagia, dysgeusia, salivary gland enlargement.
General disorders and administration site conditions: Application site reactions (e.g. irritation, inflammation, blistering, ulceration of mouth or throat, tongue or tooth discolouration, oral paraesthesia). Immune system disorders: Hypersensitivity reactions. Respiratory, thoracic and mediastinal disorders: Cough, dyspnoea. Skin and subcutaneous tissue disorders: Angioedema. |
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Action
Description:
Mechanism of Action: Hexetidine is a bactericidal and fungicidal antiseptic with broad-spectrum antimicrobial activity against gram-positive and gram-negative bacteria, yeasts (e.g. Candida albicans), and fungi. Duration: Retention on buccal tissues: 8 to 10 hours (after single oral rinse). |
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Chemical Structure
 Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 3607, Hexetidine. https://pubchem.ncbi.nlm.nih.gov/compound/Hexetidine. Accessed Apr. 30, 2024. |
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Storage
Store below 30°C. Protect from light.
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ATC Classification
A01AB12 - hexetidine ; Belongs to the class of local antiinfective and antiseptic preparations. Used in the treatment of diseases of the mouth.
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References
Bactidol (Zuellig Pharma). MIMS Malaysia. http://www.mims.com/malaysia. Accessed 03/04/2024. Buckingham R (ed). Hexetidine. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 03/04/2024. Hexetidine. UpToDate Lexidrug, Lexi-Drugs Multinational Online. Waltham, MA. UpToDate, Inc. https://online.lexi.com. Accessed 03/04/2024. Joint Formulary Committee. Hexetidine. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 03/04/2024. Oraldene (McNeil Products Limited). MHRA. https://products.mhra.gov.uk. Accessed 03/04/2024.
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