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Following exposure to HBsAg: The recommended dose for adult is: 1,000 - 2,000 I.U. intramuscularly and if necessary, the dose should be increased or repeated.
In children, inject 32 - 48 I.U. per kg of body weight.
Hepabig should be administered within 7 days after exposure to HBsAg (preferably within 48 hours).
In neonates: The recommended initial dose is 100 - 200 I.U. intramuscularly.
The first dose should be administered within 5 days after birth (preferably within 48 hours), and booster dose should be 32 - 48 I.U. per kg of body weight.
The booster dose should be administered between 2 and 3 months after the first administration.
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