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Metformin + glibenclamide (Glucovance) 250 mg/1.25 mg: Treatment of type 2 diabetes in adults as first-line therapy, when diet and exercise alone do not result in adequate glycemic control.
Metformin + glibenclamide (Glucovance) 500 mg/2.5 mg, metformin + glibenclamide (Glucovance) 500 mg/5 mg: Treatment of type 2 diabetes in adults: as second line therapy, when diet, exercise and initial treatment with metformin or glibenclamide (or another sulfonylurea) do not result in adequate glycemic control; as replacement for previous treatment with metformin and glibenclamide in patients whose glycemia is stable and well-controlled.
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