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Dyspepsia: Usual Dose: 20 mg daily for 2-4 weeks.
Gastro-Esophageal Reflux Disease (GERD): Usual Dose: 20 mg once daily for 4 weeks. Some patients may require additional 4 weeks of therapy.
Refractory Esophagitis: 40 mg daily. Maintenance therapy after healing of esophagitis is 20 mg once daily. In children, doses in the range 0.7-1.4 mg per kg body-weight daily, up to a maximum dose of 40 mg, have been given for 4-12 weeks.
Peptic Ulcer Disease: A single dose of 20 mg by mouth, or 40 mg in severe cases. Treatment is continued for 4 weeks for duodenal ulcer and 8 weeks for gastric ulcer. Where appropriate, a dose of 20 mg once daily may be given for maintenance.
NSAID-Associated Ulceration: 20 mg once daily.
Zollinger-Ellison Syndrome: Initial recommended dosage is 60 mg once daily. Or as prescribed by the physician.
Prophylaxis of Acid Aspiration During General Anesthesia: 40 mg in the evening before the surgery and 40 mg on the day of surgery, two to six hours before the procedure. Or as prescribed by the physician.
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