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Hypersensitivity to 5-FU or any ingredient of the product.
Poor nutritional state.
Dihydropyrimidine dehydrogenase enzyme deficiency.
Depressed bone marrow function (generally a leukocyte count of ≤5000/mm3 and/or a platelet count of ≤100,000/m3).
Potentially serious infections.
Pregnant or breastfeeding women.
Management of non-malignant disease.
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