Forxiga Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Dapagliflozin propanediol monohydrate

Indications/Uses

Treatment of diabetes as adjunct to diet & exercise. Monotherapy or in combination w/ other medicinal products for the treatment of type 2 DM. Prevention of new or worsening heart failure or CV death; nephropathy. Treatment of heart failure & CKD in adults.

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Dosage/Direction for Use

10 mg once daily. Type 2 DM 10 mg once daily as monotherapy or add-on combination therapy. Initial combination therapy 10 mg dapagliflozin + 500 mg metformin once daily.

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Overdosage

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Administration

May be taken with or without food: Any time of the day regardless of meals.

Contraindications

Hypersensitivity.

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Special Precautions

Reduced glucose lowering efficacy in patients w/ eGFR <45 mL/min/1.73 m². Not for the treatment of type 1 DM; diabetic ketoacidosis. Predisposing factors to ketoacidosis including low β-cell function reserve resulting from pancreatic disorders (eg, type 1 diabetes, history of pancreatitis or pancreatic surgery), insulin dose reduction, reduced caloric intake or increased insulin requirements due to infections, illness or surgery, & alcohol abuse. Discontinue or consider temporary interruption if ketoacidosis is suspected. Discontinue & institute prompt treatment if necrotizing fasciitis of perineum (Fournier's gangrene) is suspected. Concomitant use w/ medications known to cause hypoglycemia eg, insulin & insulin secretagogues (eg, sulfonylureas). Interference w/ 1,5-anhydroglucitol assay. Avoid during pregnancy (2nd & 3rd trimester). Lactation. Childn & adolescents.

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Use In Pregnancy & Lactation

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Adverse Reactions

Genital infection, UTI; back pain; pollakiuria, polyuria.

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Drug Interactions

Decreased systemic exposure w/ rifampicin. Increased systemic exposure w/ mefenamic acid. May lead to reduction in serum lithium conc due to possible increased urinary clearance of lithium.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Forxiga detailed prescribing information

Storage

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Description

View Forxiga description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antidiabetic Agents / Other Cardiovascular Drugs

ATC Classification

A10BK01 - dapagliflozin ; Belongs to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Forxiga FC tab 10 mg

Packing/Price

28's

Forxiga

Manufacturer:

AstraZeneca

Distributor:

Zuellig