Ferrous sulfate, folic acid, vitamin B-complex.
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Pharmacology: Ferrous sulfate corrects iron-deficiency anemia by providing iron necessary for the production of haemoglobin and certain iron containing enzymes and by resaturating iron storage organs. Iron is irregularly and incompletely absorbed from the gastrointestinal tract, the main sites of action being the duodenum and jejunum. Absorption is increased in conditions of iron deficiency or when given in fasting state.
Used in the prevention and treatment of iron deficiency anemia and Vitamin B complex deficiency, prenatal hematinic.
One capsule daily or as prescribed by the physician.
Care should be taken when given to patients with iron-shortage or iron-absorption diseases, hemoglobinopathies, gastrointestinal disease. As pyridoxine antagonizes levodopa, patients with Parkinson's disease treated with the latter drug should take multivitamin supplements containing pyridoxine.
Iron salts should not be given to patients receiving repeated blood transfusion or to patients with anemias not produced by iron deficiency. Oral iron should not be administered concomitantly with parenteral iron. Concomitant administration of tetracyclines and some antacids may diminish iron absorption. If treatment with both drugs is required, iron salts and tetracyclines should be administered 2-3 hours apart.
Pyridoxine Hydrochloride: Long term administration of large doses of pyridoxine is associated with development of severe peripheral neuropathies.
Folic Acid: Caution is advised in patients who may have folate-dependent tumors. Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient.
The oral administration of iron preparation sometimes produces gastrointestinal irritation and abdominal pain with nausea, vomiting, diarrhea or constipation. The faeces of patients taking iron salts may be colored black.
Treatment of Adverse Effects: In treating iron poisoning, speed is essential to block absorption of iron from the alimentary tract. However, vomiting should be taken to evaluate the number of pills remaining in the small bowel. Iron in the upper gastrointestinal tract should be precipitated by lavage with sodium bicarbonate or phosphate solution. Shock, dehydration, and acid-base abnormalities should be treated in the conventional manner.
Store at temperatures not exceeding 30°C. Protect from light.
B03AD - Iron in combination with folic acid ; Used in the treatment of anemia
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