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Absorption of iron is inhibited by magnesium trisilicate, antacids and the ingestion of eggs or milk so the iron supplements should be taken one (1) hour before or two (2) hours after eating dairy products, eggs, coffee, tea, whole-grain breads and cereals, antacids or calcium supplements.
Absorption of vitamin B12 from the gastrointestinal tract may be reduced by aminoglycosides, aminosalicylic acid, anticonvulsants, biguanides, chloramphenicol, cholestyramine, cimetidine, colchicines, potassium salts, and methyldopa. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should not be taken into account when performing assays for blood concentrations.
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