Patients should be placed on an appropriate lipid-lowering diet before receiving the fixed dose combination of Atorvastatin and Fenofibrate, and should continue this diet during treatment. The fixed dose combination of Atorvastatin and Fenofibrate should be given with meals, thereby optimizing the bioavailability of the medication.
Adults and the Elderly: Start with Atorvastatin 10 mg plus Fenofibrate 160 mg (or Atorvastatin 10 mg plus Fenofibrate 200 mg) once daily. The dosage can be titrated upwards depending on the patients' response and tolerability to treatment to a maximum of Atorvastatin 40 mg plus Fenofibrate 160 mg (or Atorvastatin 40 mg plus Fenofibrate 200 mg). Or as prescribed by the physician.
Patients with Renal and Hepatic Impairment: The fixed dose combination of Atorvastatin plus Fenofibrate is contraindicated in patients with severe renal and hepatic impairment.
Children and Adolescents: No data is available on the use of the fixed dose combination of Atorvastatin and Fenofibrate in patients under the age of 18 years. Therefore, the use of the fixed dose combination of Atorvastatin and Fenofibrate in this age group is not recommended.
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