Baclofen should be used with caution in patients who use their spasticity to maintain posture or to increase function. In patient with epilepsy, the clinical state and electroencephalogram should be monitored at regular intervals, since deterioration is seizure control and EEG have been reported occasionally in patient taking Baclofen. Because of possibility of sedation, patients should be cautioned regarding the operation of automobiles or other dangerous machinery and activities made hazardous by decreased alertness. Patient should be cautioned that CNS depressant effects of Baclofen may be additive to those of alcohol and other CNS depressants.