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The main manifestation that might be expected is excessive peripheral vasodilation with marked hypotension and in rare cases bradycardia. The therapeutic measure should include elimination of the active ingredient and reconstitution of stable cardiovascular conditions. If hypotension occurs, symptomatic treatment should be provided; the patient should be placed supine with the legs elevated, in case of accompanying bradycardia, atropine (0.5-1 mg) should be given IV. Additional fluid administration should only be initiated if under hemodynamic control to avoid cardiac overload. Sympathomimetic drugs with predominant effect on the α-adrenoreceptor may also be given.
Felodipine is dialysable to a minimal extent (approximately 9%).
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