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There is limited information on esomeprazole overdose. A patient who deliberately ingested 280 mg of esomeprazole experienced weakness, loose stools, and nausea. However, single oral doses of 80 mg esomeprazole were uneventful.
Esomeprazole is highly protein bound and is, therefore, not readily dialyzable. If overdose occurs, symptomatic and general supportive treatment should be given.
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