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Romosozumab (EVENITY) is a sterile, preservative-free solution for injection containing 105 mg/1.17 mL of romosozumab in pre-filled syringe.
Solution for Injection.
Romosozumab (EVENITY) is a sterile, preservative-free, clear to opalescent, colourless to light yellow solution, pH 5.2.
Physicochemical properties: Romosozumab is a humanised monoclonal antibody (IgG2) with high affinity and specificity for sclerostin. Romosozumab has an approximate molecular weight of 145 kDa and is produced in a mammalian cell line (Chinese hamster ovary) by recombinant DNA technology.
CAS number: 909395-70-6.
Excipients/Inactive Ingredients: Each 1.17 mL single-use pre-filled syringe contains: 0.61 mg calcium, 3.8 mg acetate, 70 mg sucrose, 0.07 mg polysorbate 20, sodium hydroxide for adjusting to pH 5.2, in Water for Injection.
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