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Isoxsuprine is a vasodilator that also stimulates beta-adrenergic receptors. It causes direct relaxation of vascular and uterine smooth muscle and its vasodilating action is greater on the arteries supplying skeletal muscles than on those supplying skin. Isoxsuprine also produces positive inotropic and chronotropic effects.
Isoxsuprine hydrochloride has been used to arrest premature labour, but drugs with a more selective action are now preferred. It has also been given in the treatment of cerebral and peripheral vascular disease.
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