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It is detected in human milk. Safety in pregnancy has not been established. It is not recommended during pregnancy, labor or delivery and in mothers who are breast-feeding.
(There was no evidence of teratogenicity in rats or rabbits studied at maternally-toxic doses of ketorolac trometamol. Prolongation of the gestation period and/or delayed parturition were seen in the rat. Ketorolac trometamol and its metabolites have been shown to pass into the fetus and milk of animals.)
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