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Dynastat

Dynastat Description

parecoxib

Manufacturer:

Pfizer

Distributor:

Zuellig
Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing
Full Prescribing Info
Description
Parecoxib (Dynastat) 40 mg vial: Drug: Each vial contains Parecoxib (as sodium) 40 mg.
Diluent: Each 2 mL ampoule contains Sodium Chloride 0.9%.
For reconstitution with 2 mL of solvent. After reconstitution, the final concentration of parecoxib (Dynastat) is 20 mg/mL.
Parecoxib sodium (hereafter referred to as parecoxib) is the prodrug for the pharmacologically active moiety, valdecoxib. Following injection, parecoxib (Dynastat) is rapidly and completely hydrolyzed enzymatically to valdecoxib.
Parecoxib (Dynastat) is chemically designated: N-[[4-(5-methyl-3-phenyl-4 isoxazolyl)phenyl]sulfonyl] propanamide, sodium salt.
C19H17N2O4SNa, M.W. = 392.41.
CAS registry no: 198470-85-8.
Parecoxib (Dynastat) is a white to off-white solid that is very soluble in water. The formulated drug product is soluble in normal (0.9%) saline at >50 mg/mL.