Duoval/Duoval Max Description

Valsartan is chemically described as N-(1-oxopenty)-N-1[[2- (1H-tetrazol-5 -yl) [1,1-biphenyl]-4-yl] methyl] L-valine. Its empirical formula is C24 H29 N5O3 and its molecular weight is 435.5. Valsartan is a white to partially white fine powder, it is soluble in ethanol and slightly soluble in water. Hydrochlorothiazide is a white, or partially white, practically odourless, crystalline powder. It is slightly soluble in water; freely soluble in sodium hydroxide solution, in n-butylamine, and in methylformamide; sparingly soluble in methanol and insoluble in ether, in chloroform, and in dilute mineral acids. Hydrochlorothiazide is chemically described as 6-chloro-3, 4-hydrochlorothiazide. Its empirical formula is C7H8CIN3O4S2 and its molecular weight is 297.73. Valsartan is non-peptide orally active specific angiotensin II antagonist acting on the AT1 receptor subtype and hydrochlorothiazide is a thiazide diuretic.
FORMULATION: Duoval: Each film-coated tablet contains: Valsartan 80 mg, Hydrochlorothiazide 12.5 mg.
Duoval Max: Each film-coated tablet contains: Valsartan 160 mg, Hydrochlorothiazide 12.5 mg.